What is Bioinformatics? (2004-2005)
Bioinformatics is defined here as an interdisciplinary research area that applies computer and information science to solve biological problems. However, this is not the only definition. The field is being defined (and redefined) at present, and there are probably as many definitions as there are bioinformaticians (bioinformaticists?).
The following references are a snapshot of the moving target named bioinformatics. They begin with a few attempts at definition, then move to articles on training, funding, and career possiblities. Suggestions for additions to this list are welcome. The list began in 2000, and 2000-2001 and 2002-2003 articles have been archived. Access to full text articles may be limited to those at the University of Minnesota.
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Defining Bioinformatics
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National Center for Biotechnology Information
What is Bioinformatics? (March 29, 2004) -
Journal of the American Medical Informatics Association
Friedman CP, Altman RB, Kohane IS, McCormick KA, Miller PL, Ozbolt JG, Shortliffe EH, Stormo GD, Szczepaniak MC, Tuck D, Williamson J. (2004)
Training the Next Generation of Informaticians: The Impact of “BISTI” and Bioinformatics—A Report from the American College of Medical Informatics
J Am Med Inform Assoc. 2004 11:167-172. -
Bioinformatics FAQ
Damian Counsell (July 19, 2005) - What is Bioinformatics? and many other questions answered
Training, Funding, and Career Possibilities
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Bioinformatics Editorials
Pavel A. Pevzner (2004) Educating biologists in the 21st century: bioinformatics scientists versus bioinformatics technicians Bioinformatics 20: 2159-2161. -
Chemistry
Becky Ham (Winter 2004) CareerView: Bioinformatics pp 12-13.
http://center.acs.org/chemistry/winter_2004.pdf -
Parasitology Today
Foote SJ, Speed T, Handman E (1998) “What can Bioinformatics do for Parasitology Research?” Parasitol Today. 1998 Sep;14(9):346-7.
http://tc.liblink.umn.edu/sfx_local?sid=Entrez:PubMed&id=pmid:17040813 -
Nature Review of Genetics
Sarah Greaves (2004) “Virtual Bioinformatics” Nature Reviews Genetics 5; doi:10.1038/nrg1329 -
Genomics and Proteomics
Michael Kane (2005) “Interdisciplinary Training in Bioinformatics, IT” Genomics & Proteomics 5(3): 10. -
Nature Review of Drug Discovery
Simon Frantz (2004) “Mining for Bioinformatics Jobs” Nature Reviews Drug Discovery 3, 281 (2004) -
Nature Biotechnology
Peter Mitchell (2004) “Bioinformatics Attracts Big Guns” Nature Biotechnology 22, 492 - 493.
K.S. Jayarama and Sabine Louet (2004) “India aims to become the main bioinformatics hub” Nature Biotechnology 22: 933. -
Nature Methods
Laura Bonetta (2004)
“Bioinformatics - from genes to pathways” Nature Methods 1, 169 - 176 (2004) -
Nature Structural and Molecular Biology
Manuel Ares Jr (2004) “Interdisciplinary research and the undergraduate biology student” Nature Structural & Molecular Biology 11, 1170 - 1172. -
Science
Lee E. Eiden (2004) “A Two-Way Bioinformatic Street” Science, 306: 1437, 2004
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Science NextWave
Karen Eilbeck (2004) “The ABCs of Bioinformatics” Science NextWave 3 September 2004
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Public Library of Science
Dawn Field, Bela Tiwari, Jason Snape (2005)
“Bioinformatics and Data Management Support for Environmental Genomics”
PLoS Biol 3(8): e297 -
Methods Inf Med
Maojo V, Martin-Sanchez F. (2004) “Bioinformatics: towards new directions for public health.” Methods Inf Med. 2004;43(3):208-14.
Knaup P, Ammenwerth E, Brandner R, Brigl B, Fischer G, Garde S, Lang E, Pilgram R, Ruderich F, Singer R, Wolff AC, Haux R, Kulikowski C. (2004)
“Towards clinical bioinformatics: advancing genomic medicine with informatics methods and tools.” Methods Inf Med. 2004;43(3):302-7. -
Biochemistry and Molecular Biology Education
C. Hack and G. Kendall (2005)
“Bioinformatics: Current Practice and Future Challenges for Life Science Education”
Biochemistry and Molecular Biology Education, 33: 82-85, 2005
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Chemical and Engineering News
Rich Mullin (2005) “Information Technology” Chemical and Engineering News 83(19) 19-24.
Rich Mullin (2005) “Drug Researchers Relent on Software” Chemical and Engineering News 83(19) 26.
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Journal of the Americal Society for Information Science and Technology
David Fenstermacher (2005) “Introduction to bioinformatics” JASIST 56: 440-446. -
Communications of the ACM
Jaques Cohen (2005) “Computer science and bioinformatics” CACM 48: 72-78. -
Microbial Cell Factories
Bansal AK (2005) “Bioinformatics in microbial biotechnology - a mini review.” Microb Cell Fact. 2005 Jun 28;4(1):19 -
Plant Physiology
Rhee SY. (2005) “Bioinformatics. Current limitations and insights for the future.” Plant Physiol. 2005 Jun;138(2):569-70. -
HHMI Bulletin
Steve Olson (2005) “Bioinformatics” HHMI Bulletin Spring 2005 -
International Journal of Toxicology
Rajpal DK. (2005) “Understanding biology through bioinformatics.” Int J Toxicol. 2005 May-Jun;24(3):147-52.
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Biometrics
Molenberghs G. (2005) “Biometry, biometrics, biostatistics, bioinformatics, ... , bio-x.” Biometrics. 2005 Mar;61(1):1-9. -
Trends in Biotechnology
Edwards D, Batley J. “Plant bioinformatics: from genome to phenome.” Trends Biotechnol. 2004 May;22(5):232-7. -
Genetics and Molecular Research
Costa Lda F. (2004) “Bioinformatics: perspectives for the future.” Genet Mol Res. 2004 Dec 30;3(4):564-74.
Leite M. (2004) “Public sphere and the sustainability of the bioinformatics promise.” Genet Mol Res. 2004 Dec 30;3(4):575-81. -
J Biochem Mol Biol.
Yu U, Lee SH, Kim YJ, Kim S. (2004) “Bioinformatics in the Post-genome Era.” J Biochem Mol Biol. 2004 Jan 31;37(1):75-82. -
Seminars in Cell and Developmental Biology
King GJ (2004). “Bioinformatics: harvesting information for plant and crop science” Semin Cell Dev Biol. 2004 Dec;15(6):721-31. -
IEEE Potentials
Doom, T.; Raymer, M.; Krane, D. “Bioinformatics” IEEE Potentials 23: 24-27 (2004) -
IT Professional
Ng, See-Kiong; Wong, Limsoon “Accomplishments and Challenges in Bioinformatics” IT Professional (2004) 6: 44-50