What is Bioinformatics?
Bioinformatics is defined here as an interdisciplinary research area that applies computer and information science to solve biological problems. However, this is not the only definition. The field is being defined (and redefined) at present, and there are probably as many definitions as there are bioinformaticians (bioinformaticists?).
The following references are a snapshot of the moving target named bioinformatics. They begin with a few attempts at definition, then move to articles on training, funding, and career possiblities. Suggestions for additions to this list are welcome. The list began in 2000, and 2000-2001, 2002-2003, 2004-2005, and 2006-2007 articles have been archived. Access to full text articles may be limited to those at the University of Minnesota.
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Defining Bioinformatics
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European Bioinformatics Institute
“Bioinformatics: An Introduction” (2008) -
Google Defines Bioinformatics
Google’s Definitions of Bioinformatics on the Web -
OneLook Dictionary Searches Defines Bioinformatics
OneLook Dictionary Search for Bioinformatics -
Bioinformatics FAQ Wiki
(23 July 2008) - What is Bioinformatics? and many other questions answered -
Wikipedia
Bioinformatics page (18 August 2008) -
American Association for Artificial Intelligence
Bioinformatics page (5 July 2008) -
University of British Columbia
Bioinformatics Education Directory
Training, Funding, and Career Possibilities
- Science
Shawna Williams (2008) “Plumbing the Green Genome” Science Career Development (25 April 2008) -
PLoS Biology
Hingamp P, Brochier C, Talla E, Gautheret D, Thieffry D, Herrman C (2008)
Metagenome Annotation Using a Distributed Grid of Undergraduate Students.
PLoS Biology 6(11): e296.
http://biology.plosjournals.org/perlserv/?request=get-document&doi=10.1371/journal.pbio.0060296 -
PLoS Computational Biology
Costa MJ, Galembeck E, Marson GA, Torres BB. (2008)
A quick guide for computer-assisted instruction in computational biology and bioinformatics.
PLoS Comput Biol. 2008 Apr 25;4(4):e1000035.
http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1000035Aoki-Kinoshita KF. (2008)
An Introduction to Bioinformatics for Glycomics Research
PLOS Comput Biol. 4(5): e1000075.
http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1000075Ragan MA, Littlejohn T, Ross, B. (2008)
Genome-Scale Computational Biology and Bioinformatics in Australia
PLoS Comput Biol 4(8): e1000068.
http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1000068 -
Journal of the American Medical Informatics Association
van Mulligen EM, Cases M, Hettne K, et al. (2008)
Training Multidisciplinary Biomedical Informatics Students: Three Years of Experience
J Am Med Inform Assoc. 15(2): 246-254.
http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=18096914
Butte AJ. (2008)
Translational Bioinformatics: Coming of Age
JAMIA Preprint August 28, 2008
http://www.jamia.org/cgi/content/abstract/M2824v1
http://tc.liblink.umn.edu/sfx_local?sid=Entrez:PubMed&id=pmid:18755990 -
Genome Biology
Stein LD. (2008)
Bioinformatics: alive and kicking
Genome Biology 2008, 9:114
http://genomebiology.com/2008/9/12/114/?mkt=175307 -
Biology Letters
Bromham L. (2009)
Putting the "bio" into bioinformatics
Biology Letters 2009, 5:391-393
http://rsbl.royalsocietypublishing.org/content/5/3/391.long -
Cambridge Quarterly Review of Healthcare Ethics
Goodman KW, Cava A. (2008)
Bioethics, Business Ethics, and Science: Bioinformatics and the Future of Healthcare
Camb Q Healthcare Ethics. 2008 Fall;17(4):361-72.
http://journals.cambridge.org/action/displayAbstract?fromPage=online&aid=2151384
http://tc.liblink.umn.edu/sfx_local?sid=Entrez:PubMed&id=pmid:18724877 -
Clinical Translational Oncology
Gomez-Lopez G, Valencia A. (2008)
Bioinformatics and cancer research: building bridges for translational research.
Clin Transl Oncol. 2008 Feb;10(2):85-95.
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Curr Opin Drug Discov Devel
Sukumar N, Krein M, Breneman CM. (2008)
Bioinformatics and cheminformatics: Where do the twain meet?
Curr Opin Drug Discov Devel. 2008 May;11(3):311-9. -
Yearbook of Medical Informatics
Yip YL. (2008)
The promise of systems biology in clinical applications.
Yearbook of Medical Informatics 2008: 102-104.
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National Library of Medicine
Gruber A, Durham AM, Huynh C, del Portillo HA, eds. (2008)
Bioinformatics in Tropical Disease Research: A Practical and Case-Study Approach
http://www.ncbi.nlm.nih.gov/books/bv.fcgi?rid=bioinfo.TOC&depth=2 -
J Clin Pathology
Sims A. (2009)
Bioinformatics and breast cancer: What can high-throughput genomic approaches actually tell us?
J. Clin. Pathol. published online 27 Jan 2009
http://jcp.bmj.com/cgi/rapidpdf/jcp.2008.060376v1
http://tc.liblink.umn.edu/sfx_local?sid=Entrez:PubMed&id=pmid:19174421